ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica

Page 1 of about 3 results

ey0019.2-23 | Miscellaneous | ESPEYB19

2.23. Effect of maternal metformin treatment in pregnancy on neonatal metabolism: evidence from newborn metabolic screening

J Estrella , V Wiley , D Simmons , TM Hng , M McLean

Diabetes Care. 2021 Nov;44(11):2536-2541. doi: 10.2337/dc21-0327. PMID: 34475030.Brief Summary: This retrospective case control study investigated changes in the metabolic profile in newborn screening of infants born to mothers who had been treated with metformin. Treatment with metformin during pregnancy was associated with subtle changes in metabolites in the newborn screening.<p class="abste...
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ey0017.2-20 | Fetal and Neonatal Cortisol Physiology | ESPEYB17

2.20. Complications of antenatal corticosteroids in infants born by early term scheduled cesarean section

K Gupta , R Rajagopal , F King , D Simmons

To read the full abstract: Diabetes Care. 2020 Apr;43(4):906–908. doi: 10.2337/dc19-2126. Epub 2020 Jan 23. PMID: 31974101Antenatal corticosteroid administration prior to planned cesarean section in early labour reduces by >50% the risk of admission to the neonatal intensive care unit for respiratory distress syndrome and transient tachypnea of the newborn. However, among pregnant women wit...
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ey0020.10-8 | New Drugs for Children with T2DM | ESPEYB20

10.8. Outcomes in children of women with type 2 diabetes exposed to metformin versus placebo during pregnancy (MiTy Kids): a 24-month follow-up of the MiTy randomised controlled trial

DS Feig , JJ Sanchez , KE Murphy , E Asztalos , B Zinman , D Simmons , AM Haqq , IG Fantus , L Lipscombe , A Armson , J Barrett , L Donovan , P Karanicolas , S Tobin , K Mangoff , G Klein , Y Jiang , G Tomlinson , J Hamilton , MiTy Kids Collaborative Group Hamilton

Brief summary: MiTy Kids is a prospective cohort study of children who were exposed to metformin during pregnancy. At 24 months, no difference was observed between those exposed to metformin and a placebo group, in BMI trajectories, mean BMI Z-score, or mean sum of skinfolds. Among those exposed to metformin, the BMI was higher among males than females.Comment: Metformin is increasingly used during pregnancy in women with T2D, but data on its lo...
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ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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